Questions? 1-800-788-1467
Important Safety Information
Do not take BETASERON® (interferon beta-1b) if you are allergic to interferon beta-1b, to another interferon beta, to human albumin, or mannitol. See additional Important Safety Information below.
Start with injection training
  • Get trained at your doctor’s office or (where state laws allow) in your own home by a BETA Nurse
  • Get your BETASERON® (interferon beta-1b) injection training kit from BETAPLUS®
  • Watch this video all the way through before injecting BETASERON for the first time
  • Get your first supply of BETASERON
If you and your doctor haven’t set up your one-on-one training yet, call BETAPLUS® at 1-800-788-1467 today.
Then set up your routine
  • Your BETA Nurse can help you
    • Set up a schedule that works for you
    • Set up a tracking plan to help you rotate your injection sites properly
  • You and your BETA Nurse, as well as your treatment team, can also discuss common side effects, and the steps you can take that may help manage them
BETAPLUS gives you lots of ways to track your therapy—on your smartphone, on your computer, or in your Treatment Journal.
Get your therapy started
  • Your doctor will tell you what dose of BETASERON to use when you begin. That dose may change based on how your body responds. This process is called titration. Titration means increasing the dosage over time so your body can adjust
  • Many doctors suggest starting BETASERON at a dose of 0.25 milliliter every other day, and gradually increasing the dose over 6 weeks to 1 milliliter every other day
  • For titration schedules, refer to your Injection Training Guide, or ask your healthcare provider
  • Do not change your dose without talking with your doctor
Always rotate your injections properly.
Talk with your doctor, nurse, or BETA Nurse if you have any side effects.

For detailed information on BETASERON, please see the Important Safety Information, full Prescribing Information, and the Injection Training Guide that comes in your BETASERON Training Kit.

“You’re involved. You’re thinking I’m going to fight this.”
a BETASERON patient

Quotes are from real patients. Models used for illustrative purposes only.

Use myBETAapp™ to help you schedule, track, and record your treatment whenever and wherever, on your mobile device or your computer.

Want to know more? Watch the video. Simply click on a question that interests you, and watch the conversation unfold.

Can someone help me with my health insurance?6:32
Can I stop taking BETASERON while on vacation?6:51
How do I track injections while on the road?6:01
Can I bring BETASERON on a plane?6:28


BETASERON® (interferon beta-1b) is a prescription medicine used to reduce the number of relapses in people with relapsing forms of multiple sclerosis (MS). This includes people who have had their first symptoms of multiple sclerosis and have an MRI consistent with multiple sclerosis. BETASERON will not cure MS but may decrease the number of flare-ups of the disease.

Important Safety Information

Do not take BETASERON (interferon beta-1b) if you are allergic to interferon beta-1b, to another interferon beta, to human albumin, or mannitol.

BETASERON can cause serious side effects, including:

Liver Problems Including Liver Failure. Symptoms of liver problems may include yellowing of your eyes, itchy skin, feeling very tired, flu-like symptoms, nausea or vomiting, bruising easily or bleeding problems. Your healthcare provider will do blood tests to check for these problems while you take BETASERON.

Serious Allergic Reactions. Serious allergic reactions can happen quickly and may happen after your first dose of BETASERON or after you have taken BETASERON many times. Symptoms may include difficulty breathing or swallowing, swelling of the mouth or tongue, rash, itching, or skin bumps.

Depression or Suicidal Thoughts. Call your healthcare provider right away if you have any of the following symptoms, especially if they are new, worse or worry you: thoughts about suicide or dying, new or worse depression (sinking feeling or sadness), new or worse anxiety (feeling uneasy, nervous or fearful for no reason), trouble sleeping (insomnia), acting aggressive, being angry, or violent, acting on dangerous impulses, hallucinations, other unusual changes in behavior or mood.

Other possible serious side effects with BETASERON include:

Heart Problems. BETASERON may worsen heart problems including congestive heart failure. Symptoms of heart problems may include swollen ankles, shortness of breath, decreased ability to exercise, fast heartbeat, tightness in chest, increased need to urinate at night, not being able to lay flat in bed.

Injection Site Problems. Serious skin reactions can happen in some people including areas of severe damage to skin and the tissue below the skin (necrosis). These reactions can happen anywhere you inject BETASERON. Symptoms of injection site problems may include swelling, redness, or pain at the injection site, fluid drainage from the injection site, breaks in your skin or blue-black skin discoloration. Change your injection site each time you inject BETASERON as it will lessen the chance of you having a serious skin reaction. Avoid injecting BETASERON into an area of the skin that is sore, reddened, infected or has other problems.

Flu-like Symptoms. BETASERON can cause flu-like symptoms including fever, chills, tiredness, sweating, muscle aches when you first start to use it. These symptoms may decrease over time. Taking medicines for fever and pain relief on the days you are using BETASERON may help decrease these symptoms.

Seizures. Some people have had seizures while taking BETASERON, including people who have never had seizures before. It is not known if the seizures were related to MS, to BETASERON, or to a combination of both. If you have a seizure after taking BETASERON call your healthcare provider right away.

Blood Problems. You may have a drop in the levels of infection-fighting white blood cells, red blood cells, or cells that help you form blood clots. If drops in levels are severe, they can lessen your ability to fight infections, make you feel tired or sluggish or cause you to bruise or bleed easily.

Risk to Pregnancy:

BETASERON can harm your unborn baby. BETASERON may cause you to lose your baby (miscarry). If you become pregnant while taking BETASERON call your healthcare provider right away. You and your healthcare provider should decide if you should continue to take BETASERON.

Most Common Side Effects:

The most common side effects of BETASERON include low white blood cell count, increases in your liver enzymes, headache, increase in your muscle tension, pain, rash, problems sleeping, stomach pain, weakness. These are not all the possible side effects of BETASERON.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. Tell your healthcare provider about all the medicines you take and your medical conditions.

Please see the full Prescribing Information, Medication Guide and
BETACONNECT™ Instructions for Use for additional information and talk to your healthcare provider.